Christopher J Sweeney Selected Research

Urinary Bladder Neoplasms (Bladder Cancer)

12/2023	Pharmacological NF-κB inhibition decreases cisplatin chemoresistance in muscle-invasive bladder cancer and reduces cisplatin-induced toxicities.
5/2011	A water soluble parthenolide analog suppresses in vivo tumor growth of two tobacco-associated cancers, lung and bladder cancer, by targeting NF-κB and generating reactive oxygen species.
4/2008	Novel agents for muscle-invasive and advanced urothelial cancer.

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Christopher J Sweeney Research Topics

Disease

120	Prostatic Neoplasms (Prostate Cancer) 04/2024 - 07/2002
76	Neoplasms (Cancer) 04/2024 - 01/2002
25	Neoplasm Metastasis (Metastasis) 03/2024 - 06/2005
8	Germ Cell and Embryonal Neoplasms (Germ Cell Tumor) 10/2021 - 09/2003
7	Fatigue 04/2024 - 05/2010
7	Carcinogenesis 11/2023 - 01/2002
7	Adenocarcinoma 01/2023 - 01/2002
6	Disease Progression 01/2023 - 08/2010
6	Carcinoma (Carcinomatosis) 12/2014 - 01/2002
4	Hypertension (High Blood Pressure) 01/2023 - 01/2016
4	Febrile Neutropenia 01/2023 - 01/2006
4	Inflammation (Inflammations) 01/2021 - 06/2014
3	Pain (Aches) 04/2024 - 10/2014
3	Urinary Bladder Neoplasms (Bladder Cancer) 12/2023 - 04/2008
3	Pancreatic Neoplasms (Pancreatic Cancer) 10/2008 - 04/2005
3	Transitional Cell Carcinoma 07/2006 - 01/2002
2	Chronic Disease (Chronic Diseases) 04/2024 - 10/2018
2	Seminoma 10/2021 - 10/2012
2	Neutropenia 10/2020 - 02/2008
2	Fibrosis (Cirrhosis) 01/2019 - 09/2003
2	Renal Cell Carcinoma (Grawitz Tumor) 01/2017 - 08/2015
2	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2017 - 04/2007
2	Teratoma (Teratoid Tumor) 01/2016 - 09/2003
2	Testicular Neoplasms (Testicular Cancer) 01/2016 - 09/2003
2	Leukemia 05/2015 - 12/2007
2	Lung Neoplasms (Lung Cancer) 05/2011 - 11/2007
2	Diarrhea 02/2008 - 02/2007
2	Breast Neoplasms (Breast Cancer) 06/2005 - 03/2002

Drug/Important Bio-Agent (IBA)

41	AndrogensIBA 04/2024 - 07/2004
37	Hormones (Hormone)IBA 04/2024 - 10/2006
31	Docetaxel (Taxotere)FDA Link 04/2024 - 06/2005
18	Prostate-Specific Antigen (Semenogelase)IBA 03/2024 - 12/2010
13	Androgen Receptors (Androgen Receptor)IBA 02/2023 - 01/2002
13	Biomarkers (Surrogate Marker)IBA 01/2022 - 05/2007
12	enzalutamideIBA 01/2023 - 05/2015
10	parthenolideIBA 10/2018 - 08/2004
8	Proteins (Proteins, Gene)FDA Link 11/2017 - 01/2002
7	abirateroneIBA 02/2023 - 12/2015
7	NF-kappa B (NF-kB)IBA 01/2021 - 03/2002
6	Cisplatin (Platino)FDA LinkGeneric 12/2023 - 04/2011
6	Testosterone (Sustanon)FDA Link 01/2023 - 01/2019
5	Messenger RNA (mRNA)IBA 12/2022 - 02/2016
5	Abiraterone AcetateIBA 01/2021 - 02/2017
5	Prednisone (Sone)FDA LinkGeneric 01/2021 - 02/2011
4	PlatinumIBA 12/2023 - 09/2003
4	cabazitaxel FDA Link 12/2022 - 01/2018
4	Transcription Factors (Transcription Factor)IBA 12/2022 - 04/2005
4	taxaneIBA 08/2021 - 02/2007
4	Bevacizumab (Avastin)FDA Link 10/2020 - 05/2010
3	Radium-223IBA 03/2024 - 01/2018
3	pertuzumabIBA 10/2023 - 02/2007
3	InterferonsIBA 02/2023 - 01/2021
3	RNA (Ribonucleic Acid)IBA 01/2023 - 05/2016
3	ChromatinIBA 12/2022 - 01/2016
3	Lysine (L-Lysine)FDA Link 12/2022 - 05/2016
3	Etoposide (VP 16)FDA LinkGeneric 10/2021 - 12/2017
3	CytokinesIBA 12/2020 - 06/2014
3	Paclitaxel (Taxol)FDA LinkGeneric 10/2020 - 02/2005
3	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 01/2020 - 07/2015
3	ParaffinIBA 01/2019 - 01/2002
3	Formaldehyde (Formol)FDA Link 01/2019 - 01/2002
3	Pemetrexed (MTA)FDA Link 07/2006 - 01/2006
3	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 07/2004 - 03/2002
3	DNA (Deoxyribonucleic Acid)IBA 11/2003 - 01/2002
2	Insulin-Like PeptidesIBA 11/2023 - 02/2014
2	Trastuzumab (Herceptin)FDA Link 10/2023 - 01/2021
2	ErbB Receptors (EGF Receptor)IBA 10/2023 - 02/2007
2	Histone DemethylasesIBA 12/2022 - 01/2018
2	atezolizumabIBA 01/2022 - 01/2022
2	Phosphotransferases (Kinase)IBA 01/2022 - 10/2014
2	ChemokinesIBA 01/2021 - 06/2014
2	Interleukin-8 (Interleukin 8)IBA 12/2020 - 06/2014
2	GlucocorticoidsIBA 01/2019 - 02/2016
2	Tumor Biomarkers (Tumor Markers)IBA 08/2016 - 02/2012
2	Diphosphonates (Bisphosphonates)IBA 02/2016 - 02/2014
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2016 - 07/2004
2	cabozantinibIBA 12/2015 - 10/2014
2	Methotrexate (Mexate)FDA LinkGeneric 06/2014 - 01/2006
2	Reactive Oxygen Species (Oxygen Radicals)IBA 05/2011 - 07/2010
2	Gemcitabine FDA Link 04/2011 - 02/2005
2	Sunitinib (Sutent)FDA Link 10/2010 - 01/2009
2	LC-1 compoundIBA 10/2008 - 12/2007
2	CarcinogensIBA 10/2008 - 11/2007
2	Celecoxib (Celebrex)FDA Link 10/2008 - 11/2007
2	Erlotinib Hydrochloride (CP 358,774)FDA Link 02/2008 - 04/2007
2	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 11/2007 - 08/2003
2	Sulindac (Copal)FDA LinkGeneric 06/2007 - 04/2005
2	SesquiterpenesIBA 10/2006 - 06/2005
2	LactonesIBA 10/2006 - 06/2005
2	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 01/2006 - 04/2005

Therapy/Procedure

81	Therapeutics 04/2024 - 07/2002
39	Castration 03/2024 - 07/2004
18	Drug Therapy (Chemotherapy) 12/2023 - 08/2003
14	Radiotherapy 03/2024 - 12/2010
13	Prostatectomy (Retropubic Prostatectomy) 01/2022 - 10/2002
3	Brachytherapy 11/2016 - 12/2010
3	Combination Drug Therapy (Combination Chemotherapy) 01/2011 - 06/2007
3	Cystectomy 04/2008 - 01/2002
2	Neoadjuvant Therapy 04/2008 - 12/2007
2	Lasers (Laser) 11/2003 - 09/2003